On the Influence of p-Nitroacetophenone on Radiation-Induced Molecular Size Changes of DNA
نویسندگان
چکیده
DNA has been irradiated in aqueous solutions with 16 MeV electron pulses (duration: 50— 100 ns). In the presence of p-nitroacetophenone (PNAP) the light scattering intensity (LSI) increased after the pulse in Arand 02-saturated solutions indicating intermolecular crosslinking. The LSI increase was greatest in Ar-sat. solutions containing t-butanol (1 mol/1). In the absence of PNAP and t-butanol DNA was degraded as indicated by a decrease of LSI. The results contribute to the understanding of radiation-induced reactions, DNA undergoes in the presence of sensitizers of high electron affinity.
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